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Adipose Tissue And Adipokines In Health And Disease

Presents a comprehensive survey of adipose tissue, its physiological functions, and its role in disease. This book discusses the role of adipose tissue in maintaining body homeostasis and the modulation of inflammatory and metabolic responses.

£103.74

Adipose Tissue and Adipokines in Health and Disease by A.P. Goldberg (Foreword), S.K. Fried (Foreword), Giamila Fantuzzi (Editor)

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Adipose Tissue Protocols

£60.48

Adipose Tissue Protocols by Kaiping Yang (Editor)

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Lamberts L-Carnitine 500mg 60 Capsules

£18.17

Lamberts L-Carnitine 500mg 60 capsules. Carnitine is an important Amino Acid made by the body from Lysine. Its most important known metabolic function is to transport long chain fatty acids into the mitochrondria of muscle cells, including those in the Myocardium, for oxidation. In this sense, Carnitine is essential for normal growth development. Cardiac muscle is especially dependent upon this mechanism as an important source of metabolic energy. In addition Carnitine has a role in the Thermogenesis (heat production) of Brown Adipose Tissue, and in the regulation of Gluconeogenesis. Lamberts L-Carnitine is presented in its free-form for maximum absorption. Carnitine primarily regulates fat burning in the body.. Suitable supplement for people doing intense physical training.. It is often taken as a supplement by slimmers. Dietary supplementation of L-Carnitine can safeguard intake of this metabolically essential substance. Because of its physiological role, L-Carnitine supplementation is also favoured by sports people. Disintegration time: Less than 1 hour. Dosage: 1 capsule each day with water or fruit juice. Amino acids are best taken half an hour before a meal or at bedtime. Do not take if pregnant or breast feeding. Suitable for vegetarians. Ingredients per tablet: L-Carnitine 500mg, Encapsulated with:Capsule Shell (Hydroxypropyl Methylcellulose), Silicon Dioxide, Magnesium Stearate, Cellulose.

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Bodydeclic Anti Cellulite Cream 150ml

£28.35

"Phytomer Unique Anti Cellulite Cream 150ml Phytomer Unique Anti Cellulite Cream offers a complete solution to the very specific problem of cellulite. This thick emulsion, covered under two separate patents, is enriched with an active ingredient with exceptional anti-cellulite properties: Algicelite. This 100% seaweed-based extract triggers three complementary actions: it prevents the formation of fat deposits, regulates the increase of adipose tissue, and facilitates the disappearance of cellulite. Reduces the appearance of excess weight. Reduces the appearance of fat reoccurrence. Helps diminish the appearance of cellulite."

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Elancyl Liporeduceur Flat Stomach 75ml

£17.50

The abdominal area and more precisely the stomach, is the favourite zone for unsightly dimples and unwanted fat : these important physical variations have a negative effect on skin elasticity and tone: vascularization, important storage of sugars, glycation phenomena. This specific physiological situation requires an adapted answer: Elancyl is proud to present the 1st Slimming, Firming Care, specially designed for the stomach zone: The Lipo-Reducer Specific Stomach. The formula of the LRSS is highly concentrated, enriched in 50% of specific slimming active ingredients compared to the Lipo-Reducer Concentrated Gel to provide an answer adapted to the physiology of the abdominal adipose tissue.

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Chemical Nutrition Pro-Cla - 120 Capsules

£19.79

Although CLA has been on the sports nutrition market for quite a while now. it has never really taken off as well as research indicated it would. and there' s a very good reason for this.The term CLA (Conjugated Linoleic Acid) is a collective one. referring to a mixture of isomers of linoleic acid. However. the studies identifying the anticatabolic properties of CLA and its ability to reduce bodyfat while enhancing lean body mass gains refer to a specific blend of only two isomers. The cis-9. trans11 and the trans10. cis-12 isomers are the only ones found to have any activity. the patent on CLA is for its weight management properties applies to a special 50:50 blend of these two isomers and no other. Due to the cost and protection offered by the patent. many companies have simply forged ahead by using cheap impure material. high in inactive isomers. yet they are claiming all the benefits referred to in the studies.Pro-CLA contains only the original patent-protected material and is provided as clear capsules. so that you may see that it is pure and devoid of the sediment normally found in other CLA products (most CLA is sold in brown capsules for this reason).It has over 80% total CLA content. -the highest on the market by far. so that you may realise the scientifically proven benefits of using the correct material.Reduces adipose tissue Increases lean mass Anti-catabolic Promotes healthy lipid profile Improves immune function

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Chemical Nutrition Sida Cordifolia - 120 Capsules

£19.49

The granddaddy of them all. ephedrine alkaloids. in whatever form (Ma Huang. ephedrine HCL. Sida Cordifolia). have been the basis for the most popular and effective fat loss formulas of all time. Ephedrine is an agonist of alpha and beta-adrenergic receptors (adrenoceptors). similar in its actions to adrenaline. It causes thermogenesis in brown adipose tissue (BAT) and skeletal muscle by way of its potent sympathomimetic stimulation (it activates the sympathetic nervous system). which results in large releases of noradrenaline. The result is an increase in energy expenditure caused by the oxidation of fat (causing a large increase in oxygen consumption). Although ephedrine bashing has become fashionable. for the most part. this is without sound justification. Obviously. there are individuals to whom ephedrine alkaloids do present a hazard. but it could be argued that flying. intense exercise or sex with a female bodybuilder offers an even greater risk. Most of the problems witnessed with ephedrine are from recreational use. as many individuals find it hard to admit that they have a problem with this. Unfortunately. as the body rapidly develops a greater tolerance. athletes using it for a pre-workout buzz often end up using huge dosages to obtain the original effect. A big issue with utilising Ma Huang (Ephedra) in a formula is obtaining consistent quality. There are numerous species of the herb Ephedra. all with different levels of ephedrine alkaloids. i.e. ephedrine. pseudoephedrine. norephedrine. norpseudoephedrine. methylephedrine and methyl-pseudoephedrine. Ephedrine itself usually accounts for between 30 and 90% of the total alkaloids present. However. alkaloid levels and ratios can even vary within the same species. dependent on such factors as time of harvest. soil quality. weather conditions and even the altitude at which it is grown. An example of this can be seen with Ephedra sinica (the commonest form used). where the cultivated form has lower alkaloid content than that of its wild counterpart. Can this degree of variation make a difference? You bet! The thermogenic activity of ephedrine and norephedrine have become well established. the other analogues are either controlled (norpseudoephedrine). carry serious health risks or are relatively inactive (the methyl isomers have very little impact on beta adrenoceptors). In the States. the FDA has now pulled the plug on norephedrine (phenylpropanolamine or PPA). The final nail in its coffin was a five-year study at Yale that linked PPA use to strokes in young women. Although several other reports have pointed the finger at PPA. this particular one is not short of a few flaws. For example. the report stated that more women suffered strokes after taking appetite suppressants than cold remedies. As the cold remedies contain far higher dosages of PPA than appetite suppressants. this tends to indicate that: A. Those using the appetite suppressants were most likely to be in a very questionable state of health. B. There was more abuse amongst those using appetite suppressants. a typical scenario amongst this sector of the public. Those fat burning products that are based on PPA typically use 20-25 mg per dosage (two dosages per day). Several OTC cold medications utilise daily dosages of around 150 mg! Was PPA more thermogenic than ephedrine? Who knows. -most users never claim to notice any anecdotal evidence of this. The existing studies were performed with mice and rats; the BAT-related thermogenic effect is more relevant to rodents than humans. In humans. skeletal muscle thermogenesis is very important to the success of the mechanism. However. there are those who prefer PPA because it suppresses appetite without any of the excitation experienced with ephedrine (*). Ironically. switching to Sida in order to avoid the legislation and bad publicity that has hounded Ma Huang has resulted in the wiser choice being made anyway. For example. L-PPA (1R. 2S Norephedrine. -the more active isomer of PPA) can represent up to 20% of Sida cordifolia’s alkaloid content. Also. this herb has demonstrated anti-obesity effects that cannot solely be attributed to its ephedrine alkaloid content. -a content which regular analysis has revealed to be comparatively more consistent than ephedra’s over the harvesting period. Although methanol extractions of the root possess significant hypoglycaemic effect; the seed extract yields an alkaloid content that will literally blow your socks off; CNP’s Sida Cordifolia is a proprietary blend of both materials

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San V12 Turbo 624g

£34.97

It started with a mental concept of the unobtainable. Vision of being able to go to the gym and surpass any feet possible in strength. endurance and performance. Realities in creating muscles that are bigger. fuller and more muscular than ever. The Vision of being UNBREAKABLE and Pure Twisted Steel has led to the birth of Fuel Injection V12. What was once believed to be unobtainable can now be yours! The birth of V12 represents what is the most versatile ergogenic and physique altering product ever formulated. V12 represents not an evolution or revolution. but more accurately depicted as a whole new way to enhance performance and to positively affect body composition. GONE. are the old school days of flooding your system with TONS of sugar in hopes of creating a decent pump. Now there is no need to worry about excess sugars and carbohydrates storing in adipose tissue. Fuel Injection V12 is light years ahead of its time and the end result is astounding increases in muscle fullness. athletic performance and lean body mass. With the birth of Fuel Injection V12. faster gains in muscle mass. strength and endurance. become now a reality. Comprised of the latest technological breakthroughs. Fuel Injection V12?s barrier-defying complex is infused with the following revolutionary and result producing compounds - Tricreatine Malate (Tri-Creatine Salt)N.A.G(N-Acetyl L-Glutamine)Betaine (Trimethylglycine)Glycocyamine Nitro Arginine(Arginine Alpha-Ketoglutarate)Taurine Together these compounds work synergistically to increase strength. endurance. recovery and vasodialation (blood flow). Also. Fuel Injection V12 increases glycogen storage. creatine production and nitrogen retention. Designed to make you feel UNBREAKABLE Fuel Injection V12 produces a "everlasting pump" with dramatic physique-altering-results in as little as 10 days. V12 PRODUCT HIGHLIGHTS: 1. Increased Lean Body Mass2. Dramatic Strength & Endurance3. Increased Protein Synthesis4. Faster Recuperation From Exercise5. Increased Vascularity6. Better Nutrient Usage7. Enhanced Endogenous Creatine Production8. Stimulates A Positive Nitrogen Balance9. Zero SUGAR and Carbs10. GUARANTEED RESULTS!HERE?S WHAT THE COMPOUNDS FOUND IN V12 ARE AND WHAT THEY DO: Tricreatine Malate: is a highly soluble creatine salt that provides much greater increase in creatine bioavailability over regular creatine monohydrate. This compound is creatine bound to malic acid. Malic acid is a naturally occurring kreb cycle intermediate. meaning that malic acid plays a crucial role in our natural energy producing cycle. Malic acid coupled with the effect of creatine as in Tricreatine Malate offers much greater ATP production over conventional creatine monohydrate. Additionally this creatine salt will not make you hold subcutaneous water like creatine monohydrate would since there is no water molecule in its chemical structure. All hydration will occur in the muscle cell. Also. Tricreatine Malate does not cause stomach discomfort and does not need to be loaded. Nitro Arginine (AKG Arginine Alpha-Ketoglutarate): works by increasing levels of nitric oxide in the body. Nitric oxide is the key component at increasing blood flow. oxygen and nutrient delivery. Nitro Arginine?s potent ability to increase blood flow by the widening of blood channels providing a constant supply of key anabolic substrates found in V12. This all will lead to shuttle additional nutrient intake directly to muscle tissue providing an ?Everlasting Pump?. N.A.G (N-Acetyl-L-Glutamine): is the acetylated version of the most abundant amino acid found in skeletal muscle tissue...glutamine. N.A.G is more stable and metabolically efficient at delivering glutamines biological effects over conventional Glutamine or Glutamine Peptides. N.A.G will play a role in increasing muscle volume. glycogen storage. growth hormone production. and it will also positively affect ones own immune system function. Betaine-Glycocyamine: These two compounds are combined at very specific ratios to aid in the natural production of creatine. They not only assist by increasing the body?s own natural production of creatine. but also increase creatine phosphate storage inside the skeletal muscle cell itself. Furthermore. glycocyamine is a tremendously powerful anti-hyperglycemic agent. rivaling the effects of the pharmaceutical drug "Metformin" aka Glucophage. Micronized Taurine: is the 2nd most abundant amino acid found in skeletal muscle. Taurine and sulfur are considered to be factors necessary for the control of many biochemical changes that take place in the aging process. It was also found to aid in the clearing of free radical wastes. Micronized Taurine aids the movement of potassium. sodium. calcium and magnesium in and out of cells and thus helps generate nerve impulses. It has cell-volumizing effects and insulin-mimicking properties. It has also been shown to aid in cardio vascular health. FUEL...

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Gaspari Size On! 1290gr

£38.65

No other Creatine cell volumizing product works as fast or as long as Size On™ Size On™ our new intra/post workout formula. is the only cell volumizer containing Creatine Gluconate. Size On™ is the first creatine with a "two staged" delivery system requiring absolutely no "loading period" and insuring fast. sustained. and maximal muscle volumization. Additionally. Size On™ is the only cell volumizer on the market with Outlast™. the first bio-engineered carbohydrate specifically designed for athletes and bodybuilders. With its quadruple redundant mitochondrial re-energizing matrix. nothing else compares to Size On™ for providing longer. harder training sessions and mind boggling pumps. Size On™ is so fast. you will literally feel and see increases in muscle belly size and fiber strength in 24-36 hours after the very first serving and unlike other cell volumizers. Size On™ guarantees Zero Stomach distress-no bloating. no abdominal discomfort. no nausea and no frequent "trips to the restroom". Sizeon™ - THE FASTEST WAY TO PUT SIZE ON! Size On™ - The Ultimate Creatine. Cell Volumizing Solution! If you were at the Mr. Olympia Contest Expo 2006 you undoubtedly heard about Gaspari Nutrition' s new Creatine Gluconate based cell volumizing solution - Size On™ There has never been a cell volumizer as technically sound and scientifically founded as Size On™ and we know all too well that this product is going to "raise the bar" for the other cell volumizers out there. What makes Size On™ so special? Well we like to say it is the "fastest acting - longest lasting. cell volumizer on the planet" but that' s a bit too general. Let' s talk about what makes Size On™ so unique and effective. Creatine Gluconate is the newest type of creatine and will probably turn out to be the most effective form to hit the supplement market. Developed by Bruce Kneller exclusively for Gaspari Nutrition. this is actually the ionic salt of a creatine ion bonded to a glucose ion. The result is that you have something that gets absorbed into the system in much of the same way glucose does (easily and almost completely). mixes very well into water. tastes great and more importantly. if likely to be the most effective creatine ever made. The reason for this is as elegant as it is simple: Most of the delivery systems used to get creatine into the blood and muscle from the GI track use a ' single stage delivery system' - they work. some work very well. but they don' t provide optimal or maximal delivery. For example Creatine Ethyl Ester (CEE) uses the ethyl ester to deliver the creatine into the bloodstream (and it does this very well) but when the molecule splits into ions. you are left with creatine (good) and ethyl alcohol/ethanol (not so good). There is no "afterburner" affect to push the creatine into the muscle cells faster or with more "force". The creatine "gets into the muscle cells" at less than an optimal or maximal rate. But with Creatine Gluconate. the glucose is the delivery system. It is absorbed well from the GI track into the bloodstream and when "the split" occurs. you end up with creatine and glucose (much better than alcohol) and glucose causes a nice insulin spike to help push itself. along with the creatine. into the muscle cells with "more force" and much faster. This two staged delivery system is unique among all creatines on the market. Just remember where you saw it first. Size On™ also contains a unique. proprietary. patent-pending oligosaccharide called Outlast™ which is a low glycemic. complex carbohydrate that has deliberately been bioengineered to have some unique properties similar to amylase/amylopectin mixes except without the "clumping" associated with those types of mixes. Gaspari Nutrition is the very first (and only) company to license Outlast™ for use in their product line and you can expect to see Outlast™ in more Gaspari products in the future. It tastes very good. mixes well into water and juices but more importantly. it is a "slow carb" - it takes a long time to be fully absorbed. In fact. it takes about 8 hours for this carb to fully make it from gut to plasma causing a constant and sustained energy supply. This is the perfect carbohydrate for those who need long term energy - triathletes. cyclists. marathoners. etc. But it also is a fantastic carb for those who need sustained energy levels beyond 45-60 minutes (like glucose or sucrose or maltodextrin provide you) to have those "mega-workouts". Interestingly...

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Hills Science Canine Nature Adult - Large Dry

£7.34

Hill's Science Plan Nature’s Best Canine Adult Large provides an ideal balance of high quality natural ingredients with added vitamins and minerals plus a natural preservative system, and a Superior Antioxidant formula to help keep your dog healthy and happy.  Studies show that neutered cats are more likely to accumulate fat rather than muscle mass. Protein & fat can both produce energy, but they are both needed to build specific structures in the body. L-carnitine stimulates the burning of fat into energy, this results in less fat being stored as fat (adipose tissue) and more used for energy. This has a sparing effect on protein, i.e. less protein is used for the production of energy and more can be available to build muscle mass (this effect has been proven in several species). In addition Hills has recently shown that increasing the intake of lysine above the level that is normally fed, helps to maintain lean muscle mass without the need to increase protein intake. Hill's Science Plan Nature’s Best Adult Large has been developed to meet the nutrient and energy needs of adult dogs one to six years of age. It contains the Hill's Superior Antioxidant Formula to help support the immune system Naturally preserved with vitamin E and rosemary for freshness and great taste. Hill's Science Plan Nature’s Best Adult Large promotes healthy skin and shiny coat.  

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